College of Engineering Design, Art and Technology has six (6) Centres headed by Directors. Centres are the base for service to the community and knowledge-transfer partnerships.
| Name of Institute/ Centre | Area of focus | Target Group | Partners | Principal Investigator /Head |
| The Institute of Heritage Conservation and Restoration | Research in Art | Researchers Students | GoU, US Embassy in Uganda, GIZ | Assoc. Prof. George Kyeyune |
| Centre for Research in Energy and Energy Conservation | Rural electrification Energy for productive use/ household use Renewable energy technologies | Students General population | GoU | Ms. Susan Abbo (External staff) |
| Centre for Research in Transportation Technologies | Green Transport Technologies | Students Business Community | GoU | Dr. Hilary Kasedde |
| Centre for Technology Development and Transfer | Solar Technology | The community Industry Students | Dr. Michael Lubwama. | |
| Centre for Geographical Information Systems (GIS) | GIS research Community Outreach Short courses | Community GIS users/ Specialists Researchers | Dr. Lydia M. KayondoNdandiko | |
| The East African Centre of Excellence in Renewable Energy and Energy Efficiency (EACREEE) | Renewable energy | East African Community member states | UNIDO, ADA and supported by the East African Community. | Dr. Mackay Okure |
| The Africa Centre of Excellence for Materials, Product Development and Nano Technology (MAPRONANO) | Nano Technology Materials development Nano medicine | Students Policy makers Industry | World Bank IUCEA MakCHS USAMRIID | Prof. J B M Kirabira |
