Transcriptomics and proteomics in human sleeping sickness pathogenesis and diagnosis ( DFG) - College of Engineering, Design, Art and TechnologyT

Funder: Germany African

Amount of funding: Euro 257,000.00

Duration: 3 years (April 2010-December 2013)

Principal Investigator: Professor Christine E. Clyaton

Team Leader Uganda: Professor John C.K. Enyaru

Co-Investigator Uganda: Dr. Enock Matovu

Collaboration: Research collaboration between Makerere University, Uganda and Zentrum für Molekulare Biologie, University of Heidelberg, Germany

Objectives: Study the immune and inflammatory reactions in African trypanosomiasis patients.Determine the effects of human environment on trypanosomes to provide information on human-trypanosome interactions. Characterise transcriptomes of infecting trypanosomes in order to access whether there are differences between parasites in CSF and blood.

Contribution to Makerere University

Equipment: ELISA reader, PCR machine,
Water bath and one WD double cabin pickup.
Molecular reagents
Technology transfer (Molecular biology techniques) to Makerere from Germany
Capacity building by training two students at Ph.D levels.

More information on the pathogenesis of African trypanosomiasis obtained with a possible spill over on identification and development of molecules for diagnosis

Funder:

Germany African

Amount:

Euro 257,000.00

Duration:

3 Years